产品货号：
Z29648
中文名称：
TWEAKR/TNFRSF12A抗体
英文名称：
Anti-TWEAKR/TNFRSF12A Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TWEAKR/TNFRSF12A Antibody |
| 指标别名 | TNF receptor superfamily member 12A;CD266;FN14;TWEAKR;TNFRSF12A |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | TNFRSF12A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Fn14 antibody was raised against a human IgG1 Fc-tagged Fn14 protein. |
| 计算分子量 | 14kDa |
| 成分 | Fn14 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Fn14 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TWEAK is a TNF family member produced by IFN-gamma-stimulated monocytes and induces multiple cell death pathways including caspase-dependent apoptosis and cathepsin B-dependent necrosis.These pathways are mediated by the binding of TWEAK by fibroblast growth factor 14 (Fn14),a member of the TNF receptor superfamily.yeast two-hybrid experiments have shown that FN14 will bind to the TNFR-associated factors TRAF1,TRAF2,TRAF3,and TRAF5,suggesting that the signaling pathway induced by TWEAK may be mediated by one or more of these adaptor molecules.Fn14 is induced during liver regeneration and is highly expressed in hepatocellular carcinomas.In addition,TWEAK induces liver progenitor cell proliferation,suggesting Fn14 may play a role in hepatocyte growth control and liver neoplasia. |
| Uniprot ID | Q9NP84 |
| 基因名全称 | Tumor necrosis factor receptor superfamily,member 12A |
| 蛋白名全称 | Tumor necrosis factor receptor superfamily,member 12A |
| 推荐稀释比 | Predicted:62kD.Observed:68kD. |
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